Research Projects


Research projects in the Biofluids Laboratory benefit from various scientific approaches and modalities that are employed to understand a specific problem or condition and answer the questions that arise in the course of conducting experiments. These tools complement each other and provide a means to assess a problem from different perspectives and make observations that covers all aspects. Click on each research tool listed below to learn more about how our research benefits from following it.

Transcatheter Aortic Valve Replacement

TAVR Modeling

A minimally invasive intervention for patients with end stage calcific aortic valve disease

Polymer Heart Valve

Prosthetic heart valve with improved hemocompatibility and extended durability

Platelet Activation Studies

Multiscale Modeling

Modelling flow-mediated platelet response at the micro- and nano-scales

Shear-Induced Platelet Activation

Study of how flow conditions in devices and pathologies affect blood platelet response

Mechanical Circulatory Support Device

Total Artificial Heart

A pulsatile bi-ventricular mechanical circulatory support device that replaces the heart in patients with end-stage congestive heart failure

Left Ventricular Assist Device

A continuous flow mechanical circulatory support device that support the left-ventricle in patients with end-stage congestive heart failure

Past Projects

Thrombogenic Potential of Prosthetic Heart Valves

Experimental evaluation of flow-mediated platelet activation in prosthetic heart valves

Mechanical Heart Valves Modeling

Computational evaluation of flow conditions due to mechanical heart valve design

Abdominal Aortic Aneurysm

Computational determination of risk of rupture in abdominal aortic aneurysms

Vulnerable Plaque

Computational determination of risk of rupture in vulnerable plaques

Smoking and Platelet Activation

Experimental evaluation of enhanced platelet activation due to cigarette smoke